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Diethylstilbestrol is generally well tolerated in female dogs. A mild side effect of diethylstilbestrol may include some blood spotting from the vagina in unspayed female dogs. Serious side effects are generally associated with。

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DES has been used to treat estrogen responsive tumors, hyperplasia of the prostate gland and in perianal gland adenomas. However, neutering (castration) is the initial。

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